Table 2.
The 20 most common modules found in the MIBiG. The functional classification, normal (N), special (S), and not functional (NF) is explained in Section 4.2. The modification refers to the reduction profile of PKS modules or epimerization of NRPS modules. The occurrence refers to the overall count in all BGCs of the MIBiG v2.
| Domain Order | Functional | Type | Modification | Occurrence |
|---|---|---|---|---|
| C-A-PCP | N | NRPS | L | 1429 |
| KS-AT-DH-KR-ACP | N | PKS | Enoyl | 895 |
| KS-AT-KR-ACP | N | PKS | Hydroxyl | 628 |
| C-A-PCP-E | N | NRPS | E | 362 |
| KS-AT-DH-ER-KR-ACP | N | PKS | Alkyl | 335 |
| KS-AT-ACP | N | PKS | Ketone | 247 |
| A-PCP | N | NRPS | L | 235 |
| C-A-PCP-TE | N | NRPS | L | 202 |
| KS-tAT_d-KR-ACP | S | PKS | Hydroxyl | 139 |
| KS-tAT_d-DH-KR-ACP | S | PKS | Enoyl | 125 |
| C-A-nMT-PCP | N | NRPS | L | 120 |
| KS-tAT_d-ACP | S | PKS | Alkyl | 71 |
| cAL-ACP | NF | PKS | - | 62 |
| KS-AT-DH-KR-ACP-TE | N | PKS | Enoyl | 61 |
| C-A-ACP | N | Mixed | L | 61 |
| C-PCP | NF | NRPS | - | 59 |
| KS-ACP | S | PKS | Ketone | 52 |
| KS-tAT_d | S | PKS | Ketone | 52 |
| KS-AT | S | PKS | Ketone | 49 |
| KS-tAT_d-DH-KR-cMT-ACP | S | PKS | Enoyl | 49 |