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. 2020 Dec 29;8(1):4. doi: 10.3390/bioengineering8010004

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Electrospinning apparatus configurations and examples of electrospun fiber features that affect glial cell behavior. (A) Electrospinning apparatus configuration for generating randomly oriented fibers on a flat plate (left) and aligned fibers on a rotating mandrel (right). Electrospinning apparatus parameters and the materials used for electrospinning can be tuned to alter fiber (B) nanotopography, (C) conductivity, (D) functionalization, or (E) drug-loading to engineer a desired cell response.