Table 3.
Clinical and laboratory characteristics of survived and died patients with sepsis (N = 88).
| Survived Patient (n = 50) |
Died Patient (n = 38) |
p Value | |
|---|---|---|---|
| Sex, male | 29 (58.0) | 18 (47.4) | 0.439 |
| Age, yrs | 71.0 (61.0–79.0) | 69.5 (54.0–83.0) | 0.879 |
| Immunocompromised patients | 18 (36.0) | 23 (60.5) | 0.039 |
| Charlson comorbidity index | 6.0 (4.0–8.0) | 5.0 (4.0–7.0) | 0.589 |
| SAPS3 score | 72.2 ± 11.6 | 83.6 ± 12.9 | <0.001 |
| SOFA score | 8.0 (7.0–11.0) | 11.0 (8.0–13.0) | 0.002 |
| Use of vasopressor on Day 1 | 35 (70.0) | 29 (76.3) | 0.676 |
| Use of invasive ventilation on Day 1 | 15 (30.0) | 21 (55.3) | 0.030 |
| Systolic BP at ICU admission | 79.0 (70.0–89.0) | 82.0 (71.0–90.0) | 0.787 |
| Diastolic BP at ICU admission | 47.5 (41.0–55.0) | 50.0 (41.0–56.0) | 0.385 |
| Heart rate at ICU admission | 124.2 ± 25.8 | 138.6 ± 28.2 | 0.014 |
| Respiratory rate at ICU admission | 28.0 (23.0–34.0) | 31.5 (26.0–38.0) | 0.076 |
| Leukocyte count, Day 1 | 8.9 (4.3–17.3) | 10.0 (3.0–16.5) | 0.768 |
| Neutrophil count, Day 1 | 7.1 (3.3–15.2) | 8.6 (2.8–14.1) | 0.714 |
| Platelet count, Day 1 | 156.5 (52.0–235.0) | 64.0 (34.0–143.0) | 0.006 |
| Lactate, Day 1 | 2.4 (1.3–3.9) | 3.4 (1.9–7.1) | 0.078 |
| Lactate, Day 3 | 1.4 (1.0–2.2) | 2.6 (1.6–5.8) | <0.001 |
| Procalcitonin, Day 1 | 10.6 (1.5–49.6) | 7.2 (2.3–27.6) | 0.383 |
| Procalcitonin, Day 3 | 3.5 (0.7–13.8) | 7.8 (2.5–40.6) | 0.022 |
| ΔProcalcitonin+ | 4 (8.0) | 14 (36.8) | 0.002 |
| Presepsin, Day 1 | 1209.0 (623.0–2559.0) | 1643.0 (777.0–3310.0) | 0.135 |
| Presepsin, Day 3 | 933.0 (638.0–1571.0) | 1965.0 (1149.0–3423.0) | 0.001 |
| ΔPresepsin+ | 16 (32.0) | 28 (73.7) | <0.001 |
SAPS3, Simplified Acute Physiology Score 3; SOFA. Sequential Organ Failure Assessment; ΔProcalcitonin+, serum procalcitonin level on day 3 minus day 1 > 0; ΔPresepsin+, plasma presepsin level on day 3 minus day 1 > 0.