Figure 1.

Study design for identifying common regulators between AD and DM. The symbols *** and * in step 3 indicate p < 0.001 (Fisher’s exact test) and p < 0.05 (t-test), respectively. AD, Alzheimer’s disease; CN_AD, AD-matched control; DM, diabetes mellitus; CN_DM, DM-matched control, rWGCNA, robust weighted gene co-expression network analysis; DEG, differentially expressed gene; QC, quality control; IQC, internal quality control; EQC, external quality control; AQC, accuracy quality control; CQC, consistency quality control; and TF, transcription factor.