Table 1.
Upregulated genes in the high-fructose corn syrup (HFCS) versus control group (n = 3 each) based on microarray analysis.
| Gene Symbol | Gene Description/Main Function of the Protein Encoded | HFCS/Control Fold Change |
|---|---|---|
| Hbb | Hemoglobin subunit beta/Involved in oxygen transport from the lung to the various peripheral tissues. | 4.686 |
| Hba1/Hba2 | Hemoglobin, alpha 1/hemoglobin alpha, adult chain 2/The two nearly identical genes provide instructions for the synthesis of alpha-globin | 1.983 |
| Cyp24a1 | Cytochrome P450, family 24, subfamily A, member 1/This enzyme helps control the amount of active vitamin D available in the body | 1.669 |
| Bcl6 | B-cell lymphoma 6/Evolutionarily conserved zinc finger transcription factor containing an N-terminal POZ/BTB domain | 1.620 |
| Plin2 | Perilipin 2/Adipose differentiation-related protein, also known as ADRP or adipophilin, belonging to the PAT family of cytoplasmic lipid droplet-binding proteins | 1.576 |
| Wsb1 | WD repeat and SOCS box-containing 1/Substrate recognition protein within an E3 ubiquitin ligase, with the capability to bind diverse targets and mediate their ubiquitinylation and proteolytic degradation | 1.549 |
| Mlph | Melanophilin/Rab effector involved in melanosome transport. | 1.509 |
| Fermt1 | Fermitin family member 1/Involved in integrin signaling and linkage of the actin cytoskeleton to the extracellular matrix | 1.502 |