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. 2020 Dec 25;12(1):19. doi: 10.3390/genes12010019

Table 7.

Drugs that alter expression TMPRSS2.

Drug Drug Groups Change References
Acetaminophen Approved downregulated 21420995
Acyline Investigational downregulated 17510436
Stanolone Illicit Investigational downregulated 12711008
Stanolone Illicit Investigational upregulated 20601956, 23708653
Estradiol Approved Investigational Vet Approved downregulated 24758408
Estradiol Approved Investigational Vet Approved upregulated 19619570
Curcumin Approved Experimental Investigational downregulated 18719366, 22258452
Cyclosporine Approved Investigational Vet Approved downregulated 20106945
Calcitriol Approved Nutraceutical upregulated 21592394, 26485663
Entinostat Investigational upregulated 26272509
Ethinylestradiol Approved downregulated 18936297
Genistein Investigational downregulated 15378649, 26865667
Metribolone Experimental downregulated 12711008
Metribolone Experimental upregulated 17010675, 21440447
Resveratrol Investigational downregulated 18586690
Selenium Approved Investigational Vet Approved upregulated 19244175
Testosterone Approved Investigational upregulated 21592394
Tretinoin Approved Investigational Nutraceutical upregulated 23830798
Valproic acid Approved Investigational upregulated 23179753, 24383497, 26272509
Zoledronic acid Approved upregulated 24714768