[Ca2+]i	intracellular free Ca2+
5-CQA	5-O-caffeoylquinic acid
ACF	aberrant crypt foci
ACE2	angiotensin-converting enzyme 2
AHP	afterhyperpolarization
AKT AP	serine/threonine kinase Akt action potential
PKB	protein kinase B
ATF-2	activating transcription factor 2
ATF-3	activating transcription factor 3
B0AT-1 BBB	sodium-dependent neutral amino acid transporter blood–brain-barrier
BE	Barrett’s esophagus
CA	caffeic acid
Ca2+ cAMP	calcium cyclic adenosine monophosphate
CART	cocaine- and amphetamine-regulated transcript
CGA	chlorogenic acid
CGRP	calcitonin gene-related peptide
CICR	calcium-induced calcium release
CNS	central nervous system
COX-2	cyclooxygenase-2
CQA	caffeoylquinic acid
CRC	colorectal cancer
CRP	C-reactive protein
DMBA	dimethylbenz(a)anthracene
DSS	dextran sodium sulfate
EC	enterochromaffin cell
EGF ENS	epidermal growth factor enteric nervous system
ERK f-EPSP	extracellular signal-regulated kinase fast excitatory postsynaptic potential
GABA	γ-aminobutyric acid
GERD	gastroesophageal reflux disease
GSK3β GST	glycogen synthase kinase 3 beta glutathione S-transferase
HE	hematoxylin/eosin
HIF-1	hypoxia-inducible factor-1
HO-1	heme oxygenase-1
HSP 70 IARC	heat shock protein 70 International Agency for Research on Cancer
IBD	inflammatory bowel disease
ICC	interstitial cells of Cajal
IKK	IkB kinase
IL-	interleukin-
iNOS	inducible nitric oxide synthase
JNK MAPK Mcl-1 MCP-1	c-Jun N-terminal kinase mitogen-activated protein kinase myeloid cell leukemia 1 methyl-accepting chemotaxis protein-1
SAPK	stress-activated protein kinase
MEK MNNG	MAPK/ERK kinase N-methyl-N-nitro-N-nitrosoguanidine
MP	myenteric plexus
ND	not detected
NF-kβ	nuclear factor-kβ
nNOS	nitric oxide synthase
NO	nitric oxide
NR	not reported
PAI-1	plasminogen activator inhibitor-1
PD	Parkinsons’s disease
PTEN PG	phosphatase and tensin homolog prostaglandin
PhIP	2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine
ROS	reactive oxygen species
RP	resting potential
RyR	ryanodine receptors
s-AHP	slow afterhyperpolarization
SARS-CoV-2	severe acute respiratory syndrome coronavirus 2
SCFA	short chain fatty acid
SCG	spent coffee grounds
s-EPSP	slow excitatory postsynaptic potential
SMP	submucous plexus
SP	substance P
spp. STAT5 TNF-R	species signal transducer and activator of transcription 5 tumor necrosis factor-receptor
TNF	tumor necrosis factor
TOPK Trp	lymphokine-activated killer t-cell-originated protein kinase-like protein tryptophan
UDP UGT1A	uridine diphosphate UDP glucuronosyltransferases
VACHT	vesicular acetylcholine transporter
VEGF	vascular endothelial growth factor
VIP	vasoactive intestinal peptide
WHO	World Health Organization
ZO-1	zonulin-1