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. 2020 Dec 24;12(1):16. doi: 10.3390/genes12010016

Figure 1.

Figure 1

Transition of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) glycoprotein D614 to G614 variant in different geographic regions. (A) Weekly ratio of D614 and G614 variants globally, and in China, Europe, North America, South Asia, and Africa. Data analyzed from COVID-19 Viral Genome Analysis Pipeline (https://cov.lanl.gov/). (B) Angiotensin 1-converting enzyme 2 (ACE2) expression level in different geographical regions. ACE2 expression score analyzed by 21 ACE2 genetic polymorphisms that significantly affect its expression level according to the current study [18]. (C) Pearson’s correlation coefficient (r) and p value between ACE2 expression score and prevalence of D614 variants in different geographical regions.