Figure 2.

IFN-α2b treatment reduces the severity of lung abnormalities in CT scans during the course of COVID-19. (A) COVID-19 cases were treated with either ARB alone (ARB, n = 24) or IFN-α2b with or without ARB (IFN, n = 53). Data points for those cases treated with IFN alone are marked as open circles. Chest CT scores were recorded relative to treatment onset, as indicated. Each data point represents a score from a CT image; p values were calculated using thenon-parametric Mann–Whitney U test with Holm’s correction for multiple comparisons. Maximum (B), final (C), and (D) % change from peak CT scores are shown with p values calculated using Wilcoxon signed-rank test.