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. 2020 Dec 29;14(1):21. doi: 10.3390/ph14010021

Table 4.

Average value ± standard deviation (in mg/L) of the concentration of PTS and PTSO reached at the limit of the microbial growth inhibition zone.

Microorganism McFarland Limit of the Microbial Growth PTS Concentration PTSO Concentration
50 mg/mL 25 mg/mL 10 mg/mL 5 mg/mL 50 mg/mL 25 mg/mL 10 mg/mL 5 mg/mL
E. coli ATCC 25922 0.5 Radius 21.5 18 15.5 11.5 28 26 23 15.5
Concentration 38.1 ± 3.3 36.9 ± 1.7 32.5 ± 1.4 30.3 ± 2.3 11.3 ± 0.9 9.5 ± 0.9 11.1 ± 0.4 11.0 ± 2.7
1 Radius 19.5 17 12.5 7 26.5 24.5 17.5 12.5
Concentration 41.9 ± 2.1 38.5 ± 1.9 38.1 ± 5.0 37.8 ± 4.9 12.2 ± 1.5 10.4 ± 0.5 12.9 ± 1.5 12.4 ± 0.7
2 Radius 18.5 17 13.5 0 23.5 21 14.5 7
Concentration 43.8 ± 1.8 38.8 ± 1.8 36.5 ± 2.6 ≥48.5 14.2 ± 1.7 12.2 ± 2.3 13.8 ± 0.9 15.2 ± 1.0
K. pneumoniae ATCC 700603 0.5 Radius 14 11 8.5 2.5 15 12.5 7.5 2.5
Concentration 53.1 ± 3.4 49.4 ± 1.9 45.3 ± 1.6 45.2 ± 1.7 19.9 ± 0.5 16.7 ± 0.6 16.3 ± 0.4 17.6 ± 0.6
1 Radius 14 11.5 6 0 13.5 11 8 1.5
Concentration 53.2 ± 4.0 48.8 ± 2.0 49.6 ± 2.5 ≥48.5 20.9 ± 0.8 17.4 ± 0.7 16.1 ± 0.6 18.0 ± 0.7
2 Radius 14 11 5.5 0.5 14 13 9 0.5
Concentration 53.7 ± 3.7 49.4 ± 3.4 50.4 ± 2.9 ≥48,5 20.7 ± 0.4 16.5 ± 0.6 15.8 ± 0.6 ≥17.9
E. faecalis ATCC 29212 0.5 Radius 17.5 15 10.5 0.5 22 19 10 1.5
Concentration 46.2 ± 4.9 42.2 ± 3.6 41.3 ± 4.6 ≥48.5 15.2 ± 0.5 13.2 ± 1.7 15.5 ± 1.1 18.0 ± 1.3
1 Radius 16.5 15 4 0 22 17 10.5 5.5
Concentration 48.5 ± 1.8 42.8 ± 1.4 52.9 ± 7.7 ≥48.5 15.4 ± 0.7 14.3 ± 2.0 15.3 ± 0.3 16.1 ± 3.5
2 Radius 15.5 14 1.5 0 20 17.5 7 0
Concentration 50.5 ± 2.0 44.3 ± 2.4 57.9 ± 4.7 ≥48.5 16.7 ± 2.1 14.0 ± 1.6 16.5 ± 2.0 ≥17.9
S. aureus ATCC 29213 0.5 Radius 22.5 19.5 15.5 14 28 26.5 25 15.5
Concentration 36.1 ± 3.7 34.0 ± 2.9 32.8 ± 2.1 26.1 ± 2.0 11.3 ± 0.7 9.3 ± 0.5 10.4 ± 0.4 10.9 ± 2.6
1 Radius 21 19 14.5 5.5 27.5 26 23.5 10.5
Concentration 39.4 ± 1.9 35.4 ± 2.2 34.2 ± 1.8 40.6 ± 8.8 11.7 ± 1.0 9.5 ± 0.7 10.9 ± 0.5 13.5 ± 1.8
2 Radio 19.5 17 12.5 6 25 26 14.5 9.5
Concentration 42.3 ± 2.2 38.6 ± 1.9 38.0 ± 2.5 39.1 ± 6.1 13.3 ± 1.7 11.1 ± 0.7 13.8 ± 2.3 14.0 ± 1.1
C. albicans ATCC 200955 0.5 Radius 41 38.5 37 34.5 42 41 38.5 35
Concentration ≤9.4 ≤5.8 ≤ 4.2 ≤8.5 ≤4.2 ≤2.6 ≤7.5 ≤2.8
1 Radius 39.5 38.5 34.5 32 42 40.5 39 36
Concentration ≤9.4 ≤5.8 ≤4.2 ≤8.5 ≤4.2 ≤2.6 ≤7.5 ≤2.8
2 Radius 38 37.5 35.5 31 40.5 38 35.5 33.5
Concentration ≤9.4 ≤5.8 ≤4.2 ≤8.5 ≤4.2 ≤2.6 ≤7.5 ≤2.8
C. krusei ATCC 6258 0.5 Radius 43 41.5 40.5 36.5 43.5 43.5 41 38.5
Concentration ≤9.4 ≤5.8 ≤4.2 ≤8.5 ≤4.2 ≤2.6 ≤7.5 ≤2.8
1 Radius 42.5 42 37.5 35.5 41.5 42 38 36.5
Concentration ≤9.4 ≤5.8 ≤4.2 ≤8.5 ≤4.2 ≤2.6 ≤7.5 ≤2.8
2 Radius 42 36 37 34 41 39.5 37.5 36
Concentration ≤9.4 ≤5.8 ≤4.2 ≤8.5 ≤4.2 ≤2.6 ≤7.5 ≤2.8

Radius: average value (in mm) of the radius of the growth inhibition halos for the 10 assays carried out with each microorganism, inoculum, concentration and organosulfur compound (see Table 2).