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Particle size, polydispersity index, and zeta potential values of non-targeted (DON-SLN) and ApoE- targeted SLNs (APOE-DON-SLN) determined at the day of preparation and at the end of a six-month period. Values presented are means ± SD (n = 3).
| Day | Formulation | Diameter (nm) | Polydispersity Index | Zeta Potential (mV) |
|---|---|---|---|---|
| 0 | DON-SLN | 104.6 ± 1.4 | 0.21 ± 0.02 | −15.2 ± 0.8 |
| 180 | 108.2 ± 0.5 | 0.28 ± 0.01 | −18.9 ± 1.1 | |
| 0 | APOE-DON-SLN | 147.5 ± 0.8 | 0.22 ± 0.01 | −9.6 ± 0.5 |
| 180 | 151.0 ± 3.5 | 0.41 ± 0.02 | −17.3 ± 0.2 |
