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. 2020 Dec 24;10(1):25. doi: 10.3390/plants10010025

Table 1.

Studies on wound healing efficacy of Moringa oleifera seeds.

S.No. A study Conducted on Moringa oleifera Seeds Findings Reference
1. Evaluation of aqueous extract of pulp and seeds of Moringa oleifera for wound healing in albino rats. The aqueous extract was studied at a dose level of 300 mg/kg body weight using resutured incision; excision and dead space wound models in rats The study included the use of systemically administered Moringa oleifera aqueous pulp and seed extract on the healing of excision, resutured incision and dead space wounds. [14]
2. Anti- Inflammatory and Healing Activity of Seed Extracts of Moringa Oleifera Harvested In Tamanrasset (Algeria) This study concluded the efficacy of the anti-inflammatory and healing power of polyphenol and saponins extracts of Moringa oleifera seeds. The study showed anti-inflammatory activity for saponins and polyphenol extracts with respective values of 28.16% and 23.61%. At the end of the study, the wounds treated with the extract of saponins demonstrated wound healing as compared to those treated with the extract of polyphenol. Madecassol®, used as a reference, showed poor wound healing compared to the wounds of tries. The saponin extract showed more effective as compared to the extract of polyphenol with significant healing power. [34]
3. Antipyretic and Wound Healing Activities of Moringa oleifera Lam. in Rats This study demonstrated significant antipyretic activity in rats using ethanolic, and ethyl acetate extracts of Moringa oleifera seeds and ethyl acetate extract of dried leaves showed significant wound healing activity (10% extracts in the form of ointment) on excision, incision and dead space (granuloma) wound models. [35]
4. Hemostatic, antibacterial biopolymers from Acacia arabica (Lam.) Willd. and Moringa oleifera (Lam.) as potential wound dressing materials The study presented the potential of the polymeric component of aqueous extracts of gum acacia and the seeds of M. oleifera in wound management. The results revealed that both biopolymers were hemostatic and hasten blood coagulation and showed shortening of activated partial thromboplastin time and prothrombin time and were non-cytotoxic. Both showed antibacterial activity against organisms known to be involved in wound infections with MIC ranging from 500–600 microg mL (−1) for GA and 300–700 microg mL (−1) for MSP. [36]
5. Evaluation of Moringa oleifera seed biopolymer-PVA composite hydrogel in wound healing dressing Hydrogel composed of polysaccharide polymer from Moringa oleifera seeds and polyvinyl alcohol (MSP/PVA) was synthesized as a wound dressing material which exhibited hemocompatibility, antibacterial activity, bacterial impermeability, antioxidant activity and iron chelation that might help in the healing of chronic wounds as well. [37]