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. 2020 Dec 30;11(1):31. doi: 10.3390/brainsci11010031

Figure 3.

Figure 3

Sleep duration in Shank3 e4-9 KO, Shank3 e4-9+/−, and control male (A) and female (B) mice. We found a statistically significant genotype x phase (p = 0.002) interaction (Table 1). Post-hoc tests showed that KO mice tended to sleep more in that active phase compared to control mice (p = 0.059). We also found statistically significant main effects of phase and sex (Table 1). Mice slept less in the active phase than in the inactive phase (p < 0.001). Female mice slept less than male mice (p < 0.001). Bars represent means ± SEM for 20 control male, 31 Shank3 e4-9+/− male, 22 KO male, 23 control female, 25 Shank3 e4-9+/− female, and 22 KO female mice.