Figure 4.

The time required to produced 8 billion doses worth of LNP formulated drug substance for the five RNA vaccine types. The times required per facility are shown on the x-axis and the five vaccine types together with their key features are shown in the table belonging to the y-axis. For this comparison it was assumed that a single facility housing a single production line at the techno-economically feasible scale is used. The error bars represent the low and high productivity scenarios which were obtained by adjusting the titre by ±20% from its baseline value of 5 g/L which corresponds to the medium scenario shown by the vertical bars of the chart.