. 2020 Dec 29;11(1):28. doi: 10.3390/biom11010028

Table 7.

Antioxidant, anti-inflammatory, and wound-healing activities detected for methanol and aqueous extracts of Balaruc cyanobacteria. - represents no significant effect; - x%, significant inhibiting effect percentage; + x%, significant increasing effect percentage.

			P. raciborskii PMC 877.14		Laspinema sp. PMC 878.14		M. vaginatus PMC 879.14		L. martensiana PMC 880.14		Nostoc sp. PMC 881.14		Aliinostoc sp. PMC 882.14		L. boryana PMC 883.14		Calothrix sp. PMC 884.14		P. couteii PMC 885.14
Bioassay		µg·mL⁻¹	MeOH	H₂O	MeOH	H₂O	MeOH	H₂O	MeOH	H₂O	MeOH	H₂O	MeOH	H₂O	MeOH	H₂O	MeOH	H₂O	MeOH	H₂O
NO secretion RAW 264.7 (antioxidant)		1	-		-		-		-		-		-		-		-		-
		5	-		-		-		-		-		-		-		-		-
		10	-		-		-		-		-		-		-		-		-
		50	-		-		-		-		-	+20 ± 2	-		-		-		-
Keratinocytes migration HaCaT (wound healing)		1	-		-		-		-		-		-		-		-		-
		5	-		-		-		-		-		-		-		-		-
		10	-		-		-		-		-		-	+22 ± 7	-		-		-
		50	-		-		-		-		-		-		-		-		-
Cytokines secretion PBMC (anti-inflammatory)	TNF α	1	-		-		-		-		-		-		-		-		-
	IL-1β		-		-		-		-		-		-		-		-		-
	IL-6		-		-		-		-		-		-		-		-		-
	IL-8		-		-		-		-		-		-		-		-		-
	TNF α	5	-		-		-		-		-		-		-		-		-
	IL-1β		-	−20 ± 5	-		-	+34 ± 3	-		-	+50 ± 8	-	+26 ± 3	-		-		-
	IL-6		-		-		-		-		-		-		-		-	−27 ± 7	-
	IL-8		-		-		-		-		-		-		-		-		-
	TNF α	10	-		-		-		-		−18 ± 4	−20 ± 4	-		-		-		-
	IL-1β		-	−28 ± 2	-		+23 ± 4	+49 ± 6	-		−26 ± 4	+52 ± 7	-	+30 ± 3	-		-	+31 ± 2	-
	IL-6		-		-		-		-		-		-		-		-	−27 ± 4	-
	IL-8		-		-		-		-		-		-		-		-		-
	TNF α	50	−19 ± 6	-	-		-		−20 ± 1	-	-		-		-		-		-
	IL-1β		−39 ± 9	−57 ± 3	-		+29 ± 3	+61 ± 2	-	+18 ± 3	−45 ± 5	+60 ± 4	-	+26 ± 5	-		-	+20 ± 2	-	−31 ± 2
	IL-6		-		-		−26 ± 5	-	-		-		-	−23 ± 4	-		-	−29 ± 3	-	−24 ± 3
	IL-8		-		-		-		-		-		-		-		-		-