Table 2.
Observed codon site substitutions including MH679991 from Singapore. Column 4, Except Isolates (Amino Acid), indicates the sequenced isolates during this study, which show a different amino acid at a given position compared to the remaining; the observed amino acid at this position is indicated in parenthesis. Although not significant at a p-value > 0.05, the mixed effects model of evolution (MEME) suggests that most codon sites had β+ > α, with the exception of codon site 444.
| Position |
MH679991 (Singapore) |
Sequenced Strains during this Study | Except Isolates (Amino Acid) | β+ | α |
|---|---|---|---|---|---|
| 3 | C | C | 314438(S) | 28.01 | 0.07 |
| 11 | F | F | 314438(Y) | 16.45 | 0.00 |
| 50 | V | V | 307424(A) | 136.69 | 0.06 |
| 129 | I | I | 310460(T) | 137.29 | 0.00 |
| 305 | S | S | 313990(P) | 144.25 | 0.00 |
| 412 | R | M | − | 4.233 | 0.15 |
| 414 | T | I | − | 5.45 | 0.00 |
| 415 | R | L | − | 7.25 | 0.00 |
| 418 | T | T | 314438(I) | 7.62 | 0.03 |
| 420 | G | W | − | 5.10 | 0.03 |
| 428 | G | V | − | 5.07 | 0.00 |
| 432 | G | V | − | 5.07 | 0.00 |
| 433 | E | G | − | 9.29 | 0.00 |
| 435 | W | L | − | 4.40 | 0.00 |
| 440 | L | F | − | 2.89 | 0.00 |
| 444 | N | Y | − | 5.75 | 20.09 |