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In vitro inhibition of the ATPase activity of LbHsp90.
| Compound | IC50 (μM) 1 |
|---|---|
| CE | 201 ± 10 |
| 1 | 83 ± 2 |
| 2 | >125 |
| 3 | 81 ± 1 |
| 4 | 48 ± 3 |
| 5 | 20 ± 2 |
| 6 | 65 ± 4 |
| 7 | >125 |
| 8 | 67 ± 3 |
| 9 | >150 |
| 10 | >125 |
| 11 | 47 ± 5 |
| PR | >500 |
1 The reported data are the mean of two experiments run in triplicates.
