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. 2021 Jan 5;13(1):33. doi: 10.3390/toxins13010033

Figure 2.

Figure 2

Homology of BmK NSPK with other scorpion toxins. (A) Multiple alignment analysis using ClustalX software showed that BmK NSPK displays over 70% similarity with reported voltage-gated potassium (Kv) channel blockers. The asterisk, dot, and colon above the sequences represent the concordance of amino acid residues in the same position: the asterisk means 100% similarity, the dot means semiconservative mutation, and the colon means conservative mutation. (B) Three-dimensional (3D) structure modeling of BmK NSPK using Buthus martensii Kaliotoxin (BmKTX, PDB code: 1BKT) as a temperate. Yellow sticks indicate the disulfide bridges.