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. 2021 Jan 22;21:92. doi: 10.1186/s12885-020-07762-9

Table 2.

Baseline characteristics of patients and their difference in curability outcomes following ESD

Patient Parameter All EGCs lesions (n = 162)
[No. (%)]
E-curative
(n = 126)
[No. (%)]
Non-e-curative
(n = 36)
[No. (%)]
p*-value
Mean age in years (±SD) 61.10 (± 8.76) 60.37 (± 8.27) 63.67 (± 10.0) 0.046
Gender 0.472
 Female 42 (25.9) 31 (24.6) 11 (30.6)
 Male 120 (74.1) 95 (75.4) 25 (69.4)
Tumor location <  0.001
 Lower third 95 (58.6) 84 (66.7) 11 (30.6)
 Middle or Upper third 67 (41.4) 42 (33.3) 25 (69.4)
Gross tumor type 0.002
 Group 1 46 (28.4) 43 (34.1) 3 (8.3)
 Group 2 116 (71.6) 83 (65.9) 33 (91.7)
Ulceration status 0.011
 Absent 135 (83.3) 110 (87.3) 25 (69.4)
 Present 27 (16.7) 16 (12.7) 11 (30.6)
Size of tumor <  0.001
 ≤ 2 cm 111 (68.5) 98 (77.8) 13 (36.1)
 >  2 cm 51 (31.5) 28 (22.2) 23 (63.9)
Differentiation <  0.001
 Differentiated 129 (79.6) 115 (91.3) 14 (38.9)
 Undifferentiated 33 (20.4) 12 (9.5) 21 (60.0)
Lauren’s category  <  0.001
 Intestinal 129 (79.6) 115 (91.3) 14 (38.9)
 Diffuse/ Mixed 33 (20.4) 11 (8.7) 22 (61.1)
Level of tumor invasion <  0.001
 Intra-mucosal tumor 132 (81.5) 124 (98.4) 8 (22.2)
 Submucosal tumor 30 (18.5) 2 (1.6) 28 (77.8)
Horizontal margin 0.010
 Negative 159 (98.1) 126 (100) 33 (91.7)
 Positive 3 (1.9) 0 (0.0) 3 (8.3)
Vertical margin 0.002
 Negative 158 (97.5) 126 (100) 32 (88.9)
 Positive 4 (2.5) 0 (0.0) 4 (11.1)
Lympho-vascular invasion 0.010
 Absent 159 (98.1) 126 (100) 33 (91.7)
 Present 3 (1.9) 0 (0.0) 3 (8.3)

ESD Endoscopic Submucosal Dissection, EGC Early Gastric Cancers, SD Standard Deviation, Group 1 = lesions with Protruding (0-I), Purely superficial flat (0-IIb) and Mixed variants with 0-IIb predominant, Group2 = Purely superficial elevated (0-IIa) or depressed (0-IIc) or mixed variants with either 0-IIa or 0-IIc predominant.

*Chi-squared independent test/Fisher’s exact test of probability or Student t-test as appropriate