Table 2.
Baseline characteristics of patients and their difference in curability outcomes following ESD
| Patient Parameter | All EGCs lesions (n = 162) [No. (%)] | E-curative (n = 126) [No. (%)] | Non-e-curative (n = 36) [No. (%)] | p*-value | 
|---|---|---|---|---|
| Mean age in years (±SD) | 61.10 (± 8.76) | 60.37 (± 8.27) | 63.67 (± 10.0) | 0.046 | 
| Gender | 0.472 | |||
| Female | 42 (25.9) | 31 (24.6) | 11 (30.6) | |
| Male | 120 (74.1) | 95 (75.4) | 25 (69.4) | |
| Tumor location | < 0.001 | |||
| Lower third | 95 (58.6) | 84 (66.7) | 11 (30.6) | |
| Middle or Upper third | 67 (41.4) | 42 (33.3) | 25 (69.4) | |
| Gross tumor type | 0.002 | |||
| Group 1 | 46 (28.4) | 43 (34.1) | 3 (8.3) | |
| Group 2 | 116 (71.6) | 83 (65.9) | 33 (91.7) | |
| Ulceration status | 0.011 | |||
| Absent | 135 (83.3) | 110 (87.3) | 25 (69.4) | |
| Present | 27 (16.7) | 16 (12.7) | 11 (30.6) | |
| Size of tumor | < 0.001 | |||
| ≤ 2 cm | 111 (68.5) | 98 (77.8) | 13 (36.1) | |
| > 2 cm | 51 (31.5) | 28 (22.2) | 23 (63.9) | |
| Differentiation | < 0.001 | |||
| Differentiated | 129 (79.6) | 115 (91.3) | 14 (38.9) | |
| Undifferentiated | 33 (20.4) | 12 (9.5) | 21 (60.0) | |
| Lauren’s category | < 0.001 | |||
| Intestinal | 129 (79.6) | 115 (91.3) | 14 (38.9) | |
| Diffuse/ Mixed | 33 (20.4) | 11 (8.7) | 22 (61.1) | |
| Level of tumor invasion | < 0.001 | |||
| Intra-mucosal tumor | 132 (81.5) | 124 (98.4) | 8 (22.2) | |
| Submucosal tumor | 30 (18.5) | 2 (1.6) | 28 (77.8) | |
| Horizontal margin | 0.010 | |||
| Negative | 159 (98.1) | 126 (100) | 33 (91.7) | |
| Positive | 3 (1.9) | 0 (0.0) | 3 (8.3) | |
| Vertical margin | 0.002 | |||
| Negative | 158 (97.5) | 126 (100) | 32 (88.9) | |
| Positive | 4 (2.5) | 0 (0.0) | 4 (11.1) | |
| Lympho-vascular invasion | 0.010 | |||
| Absent | 159 (98.1) | 126 (100) | 33 (91.7) | |
| Present | 3 (1.9) | 0 (0.0) | 3 (8.3) | 
ESD Endoscopic Submucosal Dissection, EGC Early Gastric Cancers, SD Standard Deviation, Group 1 = lesions with Protruding (0-I), Purely superficial flat (0-IIb) and Mixed variants with 0-IIb predominant, Group2 = Purely superficial elevated (0-IIa) or depressed (0-IIc) or mixed variants with either 0-IIa or 0-IIc predominant.
*Chi-squared independent test/Fisher’s exact test of probability or Student t-test as appropriate