Table 1.
Reference intervals for erythrocyte indices in healthy mice of mixed breeds
Erythrogram | ||||||||
---|---|---|---|---|---|---|---|---|
Parameters (Unit) | SWISS (mean ± SD) | BALB/c (mean ± SD) | C57BL/6 (mean ± SD) | B6D2F1 (mean ± SD) | ||||
Male | Female | Male | Female | Male | Female | Male | Female | |
BW (g) | 35.55 ± 2.66 | 29.35 ± 1.19 | 27.03 ± 1.39 | 20.80 ± 0.67 | 27.02 ± 1.22 | 20.01 ± 2.20 | 37.43 ± 1.36 | 32.75 ± 1.51 |
RBC (×106/µL) | 7.42 ± 0.85 | 7.74 ± 0.69 | 9.00 ± 0.44 | 9.08 ± 0.62 | 8.45 ± 1.15 | 8.86 ± 1.01 | 8.70 ± 1.17 | 7.99 ± 0.69 |
HCT (%) | 39.81 ± 1.64 | 40.74 ± 1.71 | 43.52 ± 2.89 | 42.57 ± 3.68 | 41.91 ± 3.41 | 37.14 ± 3.46 | 46.19 ± 5.67 | 42.73 ± 2.20 |
HGB (g/dL) | 12.92 ± 0.34 | 13.45 ± 0.71 | 13.64 ± 0.74 | 13.82 ± 1.07 | 13.13 ± 0.97 | 12.01 ± 1.02 | 13.89 ± 0.99 | 13.03 ± 0.15 |
MCV (fL) | 57.81 ± 7.79 | 54.56 ± 5.17 | 49.23 ± 1.98 | 47.73 ± 4.26 | 50.74 ± 3.18 | 42.69 ± 8.51 | 53.09 ± 0.69 | 54.09 ± 1.94 |
MCH (pg) | 18.58 ± 2.03 | 17.52 ± 2.21 | 15.56 ± 1.01 | 14.48 ± 1.04 | 16.23 ± 1.38 | 14.10 ± 2.56 | 16.19 ± 1.06 | 16.59 ± 1.28 |
MCHC (g/dL) | 31.78 ± 0.97 | 32.57 ± 1.02 | 31.77 ± 1.50 | 33.00 ± 2.60 | 31.03 ± 2.04 | 28.94 ± 1.24 | 30.43 ± 1.61 | 30.59 ± 1.19 |
RDW‐CV (%) | 15.64 ± 1.47 | 16.55 ± 1.72 | 16.34 ± 1.22 | 14.47 ± 0.88 | 15.33 ± 0.71 | 14.33 ± 1.60 | 20.80 ± 4.10 | 21.99 ± 5.29 |
RDW‐SD (fL) | 29.23 ± 0.75 | 31.16 ± 2.80 | 28.90 ± 2.11 | 27.30 ± 2.97 | 31.55 ± 1.40 | 29.09 ± 3.25 | 36.04 ± 4.75 | 39.20 ± 7.61 |
CBCs were performed in an automated veterinary hematology counter pocH‐100iV Diff™ (Sysmex® ‐ Roche). Data show means ± standard deviation (SD), calculated with GraphPad Prism version 6.01.
Abbreviations: BW, body weight; HCT, hematocrit; HGB, hemoglobin concentration; MCH, mean corpuscular hemoglobin; MCHC, mean corpuscular hemoglobin concentration; MCV, mean corpuscular volume; RBC, red blood cell; RDW‐CV, red cell distribution width ‐ coefficient of variation; RDW‐SD, red blood cells dimension width ‐ standard deviation.