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. 2020 Sep 25;178(2):375–390. doi: 10.1093/toxsci/kfaa146

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Published by Oxford University Press on behalf of the Society of Toxicology 2020.

This work is written by US Government employees and is in the public domain in the US.

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Figure 2. — Bronchoalveolar lavage parameters of lung response in the air, tobacco smoke (TS)-, crystalline silica (CS)-, and TS plus CS-exposed rats. Groups of rats were exposed to air, CS, TS, or TS plus CS and lung lavage was performed following euthanasia as described in the text. Bronchoalveolar lavage (BAL) parameters of lung response, viz, lactate dehydrogenase (LDH) activity (A), total BAL cells (B), alveolar macrophages (AMs) (C), and PMNs (D) were determined as described in the text. Data represent mean ± SE (n = 6). Statistical significance (p < .05) among the different groups of rats is represented by differences in the letters (a, b, and c) above the corresponding bars.