Table 1.
Reference | Participants | Field Strength | Findings |
---|---|---|---|
Abdul-Rahman et al28 | 32 Sz 44 HC |
3T | Sz had lower FA in left frontal arcuate fasciculus Sz had higher FA and AD in left temporal arcuate fasciculus FA and AD correlated positively with severe positive symptoms |
Boos et al29 | 126 Sz 123 nonpsychotic siblings 109 HC |
1.5T | FA in arcuate fasciculus negatively correlated with PANNS positive, negative, general, and total symptom scores Siblings had higher FA than Sz and HC |
Burns et al30 | 30 Sz 30 HC |
1.5T | Sz had lower FA in left arcuate fasciculus |
Kubicki et al31 | 21 Sz 26 HC |
1.5T | Sz had lower FA in left arcuate fasciculus |
Catani et al32 | 17 AH+ 11 AH- 59 HC |
1.5T | Sz had lower FA in left and right arcuate fasciculus AH+ had lower FA in left and right arcuate fasciculus AH- had lower FA in left and right arcuate fasciculus |
Ćurčić-Blake18 | 17 AH+ 14 AH- 14 HC |
3T | AH+ had lower FA in anterior left and right arcuate fasciculus |
de Weijer et al33 | 44 AH+ 42 HC |
3T | AH+ had lower FA in left and right arcuate fasciculus |
de Weijer et al34 | 35 Sz AH+ 35 nonpsychotic AH+ 36 HC |
3T | Sz AH+ had lower FA in left arcuate fasciculus than HC and nonpsychotic AH+ |
Hubl et al14 | 13 AH+ 13 AH- 13 HC |
1.5T | FA higher in right vs left arcuate fasciculus AH+ had higher FA in left lateral arcuate fasciculus than AH- or HC AH+ and AH- had lower FA in medial left arcuate fasciculus |
McCarthy-Jones et al35 | 18 Current AH+ 21 Remitted AH+ 40 non-auditory hallucinations 34 no hallucinations 40 HC |
1.5T | AH+ had lower FA in left arcuate fasciculus versus HC or AH- AH+ had lower FA in left arcuate fasciculus than AH- w/ hallucinations in other modalities FA of left arcuate fasciculus had nonlinear relationship with AH state |
Phillips36 | 23 Sz 22 HC |
1.5T | Sz had lower FA in left arcuate fasciculus Sz had lower volume of left arcuate fasciculus |
Rotarska-Jagiela et al37 | 24 AH+ paranoid Sz 24 HC |
3T | Sz had higher FA in arcuate fasciculus than HC FA in left arcuate fasciculus correlated positively with positive PANSS factor and AH severity |
Seok et al38 | 15 AH+ 15 AH- 22 HC |
1.5T | Both AH+ and AH- had lower FA in the anterior superior longitudinal fasciculus |
Shergill et al39 | 9 Current AH+ 17 Remitted AH+ 7 AH- 40 HC |
1.5T | Sz had lower FA in right frontal and temporal-parietal portions of superior longitudinal fasciculus FA of lateral aspect of left and right superior longitudinal fasciculus positively correlated with “propensity for auditory hallucinations” |
Note: Sz, schizophrenia; FESz, first-episode schizophrenia; HC, healthy comparison subjects; AH+, hallucinations present; AH-, no hallucinations; T, Tesla; FA, fractional anisotropy; AD, axial diffusivity; PANSS, Positive and negative Syndrome Scale.