Table 2.

ROC‐AUC and BS at 12 months from the start of treatment for the following three survival models: COX, baseline SLD and NLR as covariates; JM SLD, baseline NLR and longitudinal SLD; and JM SLD&NLR, longitudinal NLR and SLD

aROC‐AUC and BS at 12 months from start of treatment, estimated for the validation data set
Diagnostics type	AUC			BS
Model name	COX	JM SLD	JM SLD&NLR	COX	JM SLD	JM SLD&NLR
Baseline biomarkers	SLD, NLR, ECOG, PD‐L1	NLR, ECOG, PD‐L1	ECOG, PD‐L1	SLD, NLR, ECOG, PD‐L1	NLR, ECOG, PD‐L1	ECOG, PD‐L1
Longitudinal biomarkers		SLD	SLD, NLR		SLD	SLD, NLR
Cutoff time, months
0 (baseline only)	0.776	0.733	0.765	0.193	0.210	0.203
1	0.765	0.722	0.805	0.199	0.214	0.187
2	0.752	0.780	0.829	0.203	0.189	0.170
3	0.734	0.777	0.833	0.203	0.182	0.163
4	0.741	0.779	0.836	0.193	0.178	0.157
5	0.724	0.777	0.838	0.182	0.169	0.146
6	0.702	0.770	0.804	0.172	0.157	0.148