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. 2021 Jan 21;9(1):e001807. doi: 10.1136/jitc-2020-001807

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© Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY. Published by BMJ.

This is an open access article distributed in accordance with the Creative Commons Attribution 4.0 Unported (CC BY 4.0) license, which permits others to copy, redistribute, remix, transform and build upon this work for any purpose, provided the original work is properly cited, a link to the licence is given, and indication of whether changes were made. See https://creativecommons.org/licenses/by/4.0/.

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CD103+ TRMs in cSCC are situated predominantly in peritumoral areas. (A and B) Representative immunofluorescence microscopy images of cSCC showing (A) CD3 and CD103 expression and (B) CD8 and CD103 expression. In (B), the top row shows low magnification view, the middle row shows a high magnification view of a peritumoral region and the bottom row shows a high magnification view of a border between the tumor and peritumoral region. Dashed lines indicate tumor island borders. Scale bars=50 µm. cSCC, cutaneous squamous cell carcinoma; TRMs, resident memory T cells.