Table 1.
PrPC compared with PrPSc in control and PDAC tissues.
| Protein | Control | Tumor | Ratio T/C |
|---|---|---|---|
| PrPC | 32.80 ± 3.5 | 44.34 ± 5.4 | 1.35 ± 0.1 |
| PrPSc | 22.57 ± 4.1 | 50.36 ± 6.8 * | 2.26 ± 0.1 |
| Ratio PrPSc/PrPC | 0.68 ± 0.1 | 1.13 ± 0.1 * | 1.70 ± 0.1 |
Western blotting with (PrPSc) or without (PrPC) pre-treatment with proteinase K in control and PDAC tissues were compared and their ratio was provided. In PDAC tumor tissue, the increase in PrPSc surpasses at large that reported for PrPC. Values are given as the mean ± S.E.M. optical density * p < 0.05 compared with control.