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. 2021 Jan 6;13(1):37. doi: 10.3390/toxins13010037

Table 6.

Effect of dietary treatment on the levels of estradiol, leptin, GLP1, calprotectin, and zona occludens-1 in the serum from sows and piglets.

T1 T2 T3 LSD p-Value
Sows
Day 109 of gestation
Estradiol (pg/mL) 1 >1000 >1000 >1000 * *
Leptin (ng/mL) 2.0 1.7 1.5 0.43 0.11
GLP1 (pg/mL) 25.1 18.2 18.7 20.49 0.73
Calprotectin (ng/mL) 3.1 3.2 2.6 1.16 0.48
ZO-1 (ng/mL) 0.6 0.4 0.6 1.18 0.89
Day 26 weaning
Estradiol (pg/mL) 31.2 b 27.3 ab 20.9 a 7.79 0.04
Leptin (ng/mL) 1.6 b 1.3 a 1.0 a 0.31 <0.01
GLP1 (pg/mL) 24.5 10.1 14.6 18.54 0.26
Calprotectin (ng/mL) 11.2 18.2 19.6 17.71 0.56
ZO-1 (ng/mL) 0.6 0.3 0.1 0.72 0.31
Piglets
Day 26 weaning
Estradiol (pg/mL) 77.1 b 40.0 a 45.2 a 29.72 0.04
Leptin (ng/mL) 4.1 4.2 5.4 2.58 0.49
GLP1 (pg/mL) 17.5 c 12.0 b 5.1 a 5.24 <0.001
Calprotectin (ng/mL) 13.4 a 19.0 ab 20.5 b 5.77 <0.01
ZO-1 (ng/mL) 0.2 0.2 0.4 0.44 0.60

a–c Different superscripts indicate significant differences among treatments (p ≤ 0.05). T1: LoZEN from d109 gestation until d26 of lactation. T2: LoZEN from d109 gestation until farrowing and HiZEN from farrowing until d26 of lactation. T3: HiZEN from d109 gestation until d26 of lactation. 1 Measured levels were above the maximum of quantification; * Not possible to perform statistical analysis.