Table 1.

Variants, found in this study.

Gene	Total (P/LP/VUS)	Possibly Unique including Novel for the Russian Population and Described Earlier (P/LP/VUS)	Novel (P/LP/VUS)	Described in Other World Populations
LDLR	187 (38/53/95) *	67 (11/19/37)	34 (3/10/21)	120 (27/34/58)
APOB	14 (0/4/10)	6 (0/1/5)	6(0/1/5)	8 (0/3/5)
PCSK9	23 (0/4/19)	8(0/1/7)	6 (0/1/5)	5 (0/3/12)

Novel: variants found in this study for the first time. Possibly unique for the Russian population: variants found in this study and previously described only for the Russian population. (*)—for one variant it was impossible to determine the category of pathogenicity. However, it was earlier described in the literature as pathogenic.