Table 2.
Composition of NSC tablets (%, w/w).
| NSC-01 Tablet | NSC-02 Tablet | NSC-03 Tablet | NSC-04 Tablet | NSC-05 Tablet | NSC-06 Tablet | NSC-07 Tablet | Physical Mixture-07 Tablet | |
|---|---|---|---|---|---|---|---|---|
| NSC-01 | 7 | - | - | - | - | - | - | - |
| NSC-02 | - | 15 | - | - | - | - | - | - |
| NSC-03 | - | - | 21 | - | - | - | - | - |
| NSC-04 | - | - | - | 18 | - | - | - | - |
| NSC-05 | - | - | - | - | 21 | - | - | - |
| NSC-06 | - | - | - | - | - | 21 | - | - |
| NSC-07 | - | - | - | - | - | - | 10 | - |
| Physical mixture-07 | - | - | - | - | - | - | - | 10 |
| CCS | 9 | 8 | 8 | 7 | 8 | 8 | 9 | 9 |
| L-HPC | 21 | 21 | 18 | 18 | 18 | 18 | 21 | 21 |
| MCC | 21 | 20 | 18 | 18 | 18 | 18 | 21 | 21 |
| SMCC | 21 | 18 | 16 | 16 | 16 | 16 | 19 | 19 |
| IM | 21 | 18 | 18 | 16 | 18 | 18 | 21 | 21 |
| SSF | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| Total weight | 150 mg | 160 mg | 170 mg | 220 mg | 170 mg | 170 mg | 150 mg | 150 mg |
Abbreviations: NSC, nanoporous silica entrapped lipid-drug complex; CCS, Croscarmel-lose sodium; L-HPC, low-substituted hydroxypropyl cellulose; MCC, microcrystalline cellulose; SMCC, silicified microcrystalline cellulose; IM, isomalt; SSF, sodium stearyl fumarate.