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. 2021 Jan 23;66(7):659–669. doi: 10.1038/s10038-021-00902-4

Table 5.

Influence of participant’s attitudes, knowledge, and experience on preferences toward in-person GC model and duration

Preferences toward pretest GC model Preferences toward pretest GC duration (minutes in length)
n = 110a In-person GC (n = 92) Classroom or group GC (n = 15) n = 112b ≥30c (n = 33) <15 (n = 17)
Number Number (%) p value Number (%) p value Number Number (%) p value Number (%) p value
Experience
Prenatal testing in a prior pregnancy 0.050 0.959 0.363 0.946
 Yes 7 4/7 (57.1) 1/7 (14.3) 7 1/7 (14.3) 1/7 (14.3)
 No 103 88/103 (85.4) 14/103 (13.6) 105 32/105 (30.5) 16/105 (15.2)
Had someone in their vicinity with T21 or talked with people of T21 0.837 0.853 0.017 0.289
 Yes 39 33/39 (84.6) 5/39 (12.8) 39 17/39 (43.6) 4/39 (10.3)
 No 71 59/71 (83.1) 10/71 (14.1) 73 16/73 (21.9) 13/73 (17.8)
Prenatal testing in this pregnancy 0.587 0.417 0.328 0.099
 None 62 50/62 (80.7) 10/62 (16.1) 64 21/64 (32.8) 8/64 (12.5)
 NIPT 25 23/25 (92.0) 1/25 (4.0) 25 4/25 (16.0) 2/25 (8.0)
 MSS 22 18/22 (81.8) 4/22 (18.2) 22 8/22 (36.4) 7/22 (31.8)
 AC/CVS 1 1/1 (100.0) 0/4 (0.0) 1 0/1 (0.0) 0/1 (0.0)
Attitudes
Preference on brochures of prenatal testing at the first visit 0.687 0.645 0.476 0.763
 Wanted to receive 75 62/75 (85.7) 11/75 (14.7) 76 24/76 (31.6) 11/76 (14.5)
 No or neither or don’t know 35 30/35 (82.7) 4/35 (11.4) 36 9/36 (25.0) 6/36 (16.7)
Planned prenatal testing at questionnaire 0.157 0.292 0.561 0.790
 No testing 32 25/32 (78.1) 6/32 (18.8) 33 11 /33 (33.3) 6 /33 (18.2)
 Undecided 33 31/33 (93.9) 2/33 (6.1) 33 11/33 (33.3) 4/33 (12.1)
 Will have testing 45 36/45 (80.0) 7/45 (15.6) 46 11/46 (23.9) 7/46 (15.2)
Needed agreement with the partner for prenatal testing 0.229 0.028 0.855 0.043
 Yes 86 70/86 (81.4) 15/86 (17.4) 87 26/87 (29.9) 10/87 (11.5)
 No or neither or don’t know 24 22/24 (91.7) 0/24 (0.0) 25 7 /25 (28.0) 7 /25 (28.0)
Want to have GC with husband 0.744 0.725 0.157 0.171
 Yes 100 84/100 (84.0) 14/100 (14.0) 102 32/102 (31.4) 14/102 (13.7)
 No 10 8/10 (80.0) 1/10 (10.0) 10 1/10 (10.0) 3/10 (30.0)
Knowledge
Aware of prenatal testing before this pregnancy 0.275 0.397 0.037 0.183
 Yes 95 78/95 (82.1) 14/95 (14.7) 97 32/97 (33.0) 13/97 (13.4)
 No 15 14/15 (93.3) 1/15 (6.7) 15 1/15 (6.7) 4/15 (26.7)
Aware of GC 0.877 0.312 0.140 0.056
 Yes 26 22/26 (84.6) 2/26 (7.7) 27 11/27 (40.7) 1/27 (3.7)
 No 84 70/84 (83.3) 13/84 (15.5) 85 22/85 (25.9) 16/85 (18.8)
Understanding of mechanism of T21 0.933 0.724 0.617 0.054
 Not an inherited disease 56 47/56 (83.9) 7/56 (12.5) 57 18/57 (31.6) 5/57 (8.8)
 Inherited disease or don’t know 54 45/54 (83.3) 8/54 (14.8) 55 15/55 (27.3) 12/55 (21.8)
Understanding of average of life expectancy of T21 0.425 0.200 0.629 0.027
 ≥40 years old 46 40/46 (87.0) 4/46 (8.7) 47 15/47 (31.9) 3/47 (6.4)
 <40 years old or don’t know 64 52/64 (81.3) 11/64 (17.8) 65 18/65 (27.7) 14/65 (21.5)
Recognition of MAE-related disorders 0.194 0.243 0.208 0.723
 Yes 102 84/102 (82.4) 15/102 (14.7) 103 32/103 (31.1) 16/103 (15.5)
 No 8 8/8(100.0) 0/8 (0.0) 9 1/9 (11.1) 1/9 (11.1)

AC amniocentesis, CVS chorionic villus sampling, GC genetic counseling, NIPT noninvasive prenatal testing, MSS maternal serum screening, MAE maternal age effect, T21 trisomy 21

aFour participants who answered “don’t know” to the questions about preference for GC models were excluded from this analysis

bTwo participants who answered “don’t know” to the questions about preference for duration of pretest GC time were excluded from this analysis

cIncludes participants who preferred 30–59 min only, as no participants preferred ≥60 min