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Receiver operating characteristic (ROC) curves investigate the diagnostic and staging power of amount combined of the miRNAs. (a) Plasma levels of miR-210 with miR-152 discriminate breast cancer (BC) patients from healthy individuals—area under the curve (AUC) = 0.7542; cut-off value of 0.9571. (b) Plasma levels of miR-210 with miR-152 discriminate advanced stage of BC patients from early/intermediate stage of BC patients (AUC = 0.7733; cut-off value of 2.660).
