Table 1.

Discrete event simulation input parameters before diagnosis*

Input parameters	Direct costs, $	Probability	Time, d	Utility	Range	Sources
Screening costs
Mammography	187	N/A	0.25	—	—	Plevritis et al., 2006 (16), and Mittmann et al., 2015 (17)
Magnetic resonance imaging	631	N/A	0.5	—	—	Mittmann et al., 2015 (17), and Pataky et al., 2013 (30)
Clinical diagnosis	229	N/A	0.5	—	—	de Bock et al., 2013 (31)
Invasive work-up		0.15		—	—	Mittmann et al., 2014 (29)
Needle biopsy	761	0.82	1	—	—	Plevritis et al., 2006 (16), and Mittmann et al., 2014 (29)
Excisional biopsy	1687	0.18	2	—	—	Plevritis et al., 2006 (16), and Mittmann et al., 2014 (29)
Non invasive work-up	455	1.0	0.25	—	—	Plevritis et al., 2006 (16), and Mittmann et al., 2014 (29)
Assumed baseline utilities
Breast cancer free	NA	1.0	N/A	0.84	(0.76, 1.00)	Cappelli et al., 2001 (20), Antoniou et al., 2003 (21), and Ara and Wailoo, 2011 (22)
Undiagnosed breast cancer	NA	1.0	N/A	0.84	(0.76, 1.00)	Cappelli et al., 2001 (20), Antoniou et al., 2003 (21), and Ara and Wailoo, 2011 (22)

*N/A = not applicable.