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Endogenous contrast agents for PAI (NIR-I = 650–1000 nm; NIR-II = 1000–1700 nm [32]).
| Chromophore | Wavelenght Window | Clinical Interest |
|---|---|---|
| Melanin | NIR-I and NIR-II | Skin cancer |
| Hemoglobin (Oxy-Deoxy) | NIR-I | Ischemia, hypoxia or hypoxemia, tumor angiogenesis |
| Lipids [33] | NIR-II | Arterial plaques monitoring, diabetes, obesity, fatty liver disease |
| Collagen [34] | NIR-II | Orthopedics, dermatology, and cardiology |
