Table 1.
List of ferroptosis genes in human dorsolateral prefrontal cortex development.
| Gene Symbol |
Trajectory Group |
Module Assigned |
Module Description |
Cellular Group |
|---|---|---|---|---|
| FR-inducing genes | ||||
| NCOA4 | Non- transitional |
M5 | RNA processing | No cellular specificity |
| ATF4 | M6 | RNA processing | ||
| VDAC2 | ||||
| VDAC3 | ||||
| POR | M7 | RNA processing | ||
| LPCAT3 | M9 | Chromosome organization | ||
| MAP1LC3B | Postnatal | M16 | Ribose phosphate metabolic process |
Excitatory neuron |
| TFRC | ||||
| MAP1LC3A | M17 | Macroautophagy | ||
| HMOX1 | M18 | Immune effector process | Non-neuronal cell | |
| YAP1 | ||||
| EPAS1 | M19 | Synaptic signaling | Excitatory neuron, Non-neuronal cell | |
| TF | ||||
| FR-suppressing genes | ||||
| GSS | Non- transitional |
M6 | RNA processing | No cellular specificity |
| PROM2 | M9 | Chromosome organization | ||
| AIFM2 | M12 | Regulation of ion transmembrane transport | ||
| FTL | M14 | Mitochondrion organization | ||
| GPX4 | ||||
| SLC3A2 | ||||
| NFE2L2 | Postnatal | M18 | Immune effector process | Non-neuronal cell |
| SLC7A11 | ||||
| GCLC | M19 | Synaptic signaling | Excitatory neuron, Non-neuronal cell | |