Table 2.

Secondary structural elements of mutant antithrombin. The percentage of residues involved in the different secondary structure classes for the beta-wild type (WT) and variant antithrombins M315N/V317T, L146T, and F77N. The results calculated for the WT PDB structure 1T1F are reported for comparison. (Here, unresolved residues in PDB are considered as coil elements).

Mutants	Alpha-Helix	Beta-Sheet	Turn	Coil
	%	%	%	%
WT	27 ± 3	25 ± 3	17 ±4	31 ± 3
M315N/V317T	29 ± 2	22 ± 2	17 ± 4	32 ± 1
L146T	29 ± 2	23 ± 2	17 ± 4	31 ± 2
F77N	30 ± 2	23 ± 2	17 ± 4	30 ± 3
pdb:1T1F	28	27	25	20