Table 1.
Protein/lipid interactions detected by the lipid overlay assay.
| PKCZ | PKCι | |
|---|---|---|
| PI | − | − |
| PI(3)P | − | ++ |
| PI(4)P | − | ++ |
| PI(5)P | − | ++ |
| PI(3,4)P2 | − | − |
| PI(3,5)P2 | − | − |
| PI(4,5)P2 | − | − |
| PI(3,4,5)P3 | − | − |
| PA | ++ | ++ |
| LPA | − | − |
| PC | − | − |
| LPC | − | − |
| PS | ++ | ++ |
| PE | − | − |
| PG | + | + |
| DAG | − | − |
| S | − | − |
| S1P | − | − |
| SPC | − | − |
| PHS | − | − |
| CE | − | − |
| SM | − | − |
| SM4 | − | + |
| GM1 | − | − |
++ strong signal, + weak signal, and − no signal. PKC: protein kinase C, PIP: phosphatidylinositol monophosphate, PA: phosphatidic acid, LPA: lysophosphatidic acid, PC: phosphatidylcholine, LPC: lysophosphocoline, PS: phosphatidylserine, PE: phosphatidylethanolamine, PG: phosphatidylglycerol, DAG: diacylglycerol, S: sphingosine, S1P: sphingosine-1-phosphate, SPC: sphingosylphosphorycholine, PHS: phytosphingosine, CE: ceramide, SM: sphingomyelin, SM4: sulfatide, and GM1: monosialoganglioside.