Table 4.
Upstream regulators that were predicted to be activated (+) or inhibited (--) in wooden breast myopathy (WB) proteomics (from Kuttappan et al. [2]) with the resulting prediction when the FE proteomics dataset from high and low feed efficiency (FE) Pedigree Broilers males [11] was overlaid on the WB upstream regulator network. The designation ‘no’ indicates that no prediction was made with the FE overlay (projection of FE dataset onto WB myopathy dataset).
| Upstream Regulator | WB | FE Overlay | Upstream Regulator | WB | FE Overlay |
|---|---|---|---|---|---|
| ANGPT2 | + | no | RICTOR | -- | no |
| EGFR | + | no | PPARGC1α | -- | no |
| XBP1 | + | no | AHR | -- | no |
| TGFB1 | + | + | ARNT | -- | no |
| NFE2L2 | + | + | ESRRG | -- | no |