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ECs’ growth modulated by hypoxic micro-environmental conditions. Cell density after 48 h in normoxia or hypoxia: Cells were seeded at 0 h in the same number. Growth of healthy ECs is a little slower upon hypoxia vs. normoxia, oppositely to cancer derived ECs, whose growth is higher in hypoxic conditions as compared to normoxia. (A)—healthy ECs, normoxia; (B)—healthy ECs, hypoxia; (C)—cancer-derived ECs, normoxia; (D)—cancer-derived ECs, hypoxia; magnification 4×.
