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. 2021 Jan 7;22(2):529. doi: 10.3390/ijms22020529

Figure 4.

Figure 4

The influence of adipocytes on melanoma proliferation, epithelial–mesenchymal transition, cell invasion, metastasis, angiogenesis, and drug resistance. A detailed description of the shown processes is present in the text. Abbreviations: FABP4, fatty acid binding protein 4; PPARy, peroxisome proliferator-activated receptor γ; miR-214-3p, microRNA 214-3p; FASN, fatty acid synthase; P-g, P-glycoprotein; HGF, hepatocyte growth factor; VEGF, vascular endothelial growth factor; IL-6, interleukin 6; MMP9, matrix metalloproteinases 9; FAO, fatty acid oxidation; MMPs, matrix metalloproteinases.