Table 3.

Results of SBRT for HCC (small tumors) in the largest retrospective studies and systematic reviews.

Author	Study Design	Number of Patients	Lesion Size	Median Follow-Up (Months)	LC After 3 Years (%)	3 Year OS (%)	Relevant Toxicity
Sanuki [19]	Retrospective	185	GTV 7.64 mL	24	91	70	2 pts. Grade 5
Mathew [20]	Retrospective	297	42% > 3 cm		86.7	39	Worsening of C–P score by ≥2 points in 15.9%
Dobrzycka [21]	Systematic review	973	Average diameter 23 mm	11.5–41.7	93	73.4	5.3% Grade ≥3
Rim [22]	Systematic review	1950	Average diameter 33 mm		83.9	48.3	4.7% Grade ≥3