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Schematic diagram of the critical path. (A) phosphatidylinositol-3-kinase (PI3K)-Akt signaling pathway; (B) FOXO signaling pathway; (C) mitogen-activated protein kinases (MAPK) signaling pathway; (D) T cell receptor signaling pathway. The dashed rectangle represent the pathways. The targets marked by a star represent the target of RDNI.
