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. 2021 Jan 23;268(9):3059–3071. doi: 10.1007/s00415-021-10406-y

Table 1.

Neurological symptoms, manifestations, and complications in association with COVID-19

Neurological symptoms Neurological manifestations and complications
Gustatory dysfunctions (38.5%) Stroke (2.3%)
Olfactory dysfunctions (hyposmia/anosmia) (35.8%) Epilepsy and seizures (0.9%)
Myalgia (19.3%) Cerebral venous (sinus) thrombosis (0.3%)
Headache (14.7%) Meningitis, encephalitis, meningoencephalitis
Altered mental status (9.4%) [5, 117] Guillan–Barré syndrome
Dizziness (8.77%) Miller Fisher syndrome/Bickerstaff’s encephalitis [118]
Nausea and vomiting (4.6%) [51, 119] Acute myelitis
Neuralgia (2.3%) [32, 120] Posterior reversible encephalopathy syndrome (PRES)
Ataxia (0.3%) [121, 122] Acute hemorrhagic necrotizing encephalopathy [123, 124]
Myoclonus [125, 126] Acute demyelinating encephalomyelitis (ADEM)-like pathology [127, 128]
Diplopia [129] Posthypoxic necrotizing leukoencephalopathy [130]
Vision loss [131] CNS vasculitis [117]
Stupor [2] Acute cerebellitis [132]
Meningism [133] Movement disorders [134]
Dysexecutive syndrome [135] Intensive-care-unit acquired neuropathy [2]
Bilateral leg stiffening [136] Rhabdomyolysis [137]
Sustained upward gaze [136] Critical illness myopathy [138, 139]
Necrotizing autoimmune myositis (NAM) [140]
Acute mesenteric ischemia [141]

This table summarizes different neurological symptoms, manifestations, and complications observed in association with COVID-19. Symptoms, manifestations, and complications written in bold are each addressed separately in the manuscript. All other symptoms, manifestations, and complications have been reported or at least mentioned in articles regarding COVID-19; however, insufficient data restrict detailed information.

The percentage in parentheses indicates the prevalence of the neurological symptom/manifestation/complication.