Table 3.
Immunogenicity (HLA class I) analysis of S-protein epitopes.of seven HCoVs.
| Sl. no | Human CoVs strain name | Common B and T-cell epitopes sequence | Epitope (peptide) length | Immunogenicity (HLA class I) score |
|---|---|---|---|---|
| 1 | SARS-CoV-2 | VRQIAPGQT | 9 | 0.0849 |
| 2 | YQAGSTPCN | 9 | −0.11862 | |
| 3 | FQPTNGVGF | 9 | 0.1157 | |
| 4 | ILPDPSKPS | 9 | −0.33629 | |
| 5 | SARS-CoV | VRQIAPGQT | 9 | 0.0849 |
| 6 | FSPDGKPCT | 9 | −0.19214 | |
| 7 | MERS-CoV | LLSGTPPQV | 9 | −0.06928 |
| 8 | YGTDTNSVC | 9 | −0.04887 | |
| 9 | LTPRSVRSV | 9 | −0.12674 | |
| 10 | YQNISTNLP | 9 | −0.00468 | |
| 11 | LGNSTGIDF | 9 | 0.02641 | |
| 12 | HCoV-OC43 | YRRKPDLPN | 9 | −0.20596 |
| 13 | FKPQPAGVF | 9 | −0.04141 | |
| 14 | FTGPYKCPQ | 9 | −0.25874 | |
| 15 | HCoV-NL63 | VKSGSPGDS | 9 | −0.14958 |
| 16 | VRPRNSSDN | 9 | −0.24021 | |
| 17 | HCoV-HKU1 | ITAYDPRSC | 9 | −0.03284 |
| 18 | YNSPSSSSS | 9 | −0.61797 | |
| 19 | YYYPEPISD | 9 | 0.09036 | |
| 20 | HCoV-229E | LPRSGSRVA | 9 | −0.2046 |