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Mechanisms of MC in delaying glucose absorption. In the small intestine, MC agents delay the digestion and absorption of food because of the inhibitory activity in α-amylase, pancreatic lipase, and α-glucosidase. MC agents also activate PI3K, which is associated with less glucose absorption in the jejunum epithelium, and suppress GLUT2, which is associated with decreased reabsorption of glucose in the kidney.
