Table 3.
Clinical trials of FMT involving in nervous and mental disease.
| NCT number | Conditions | FMT route | Phases | Status | Locations |
|---|---|---|---|---|---|
| NCT02255617 | Hepatic encephalopathy | Colonoscopy & enema | Phase 1, phase 2 | Completed | Canada |
| NCT02636647 | Hepatic encephalopathy | Enema | Phase 1 | Completed | United States |
| NCT03420482 | Hepatic encephalopathy | Capsules | Phase 2 | Recruiting | United States |
| NCT03152188 | Hepatic encephalopathy | Capsules | Phase 1 | Completed | United States |
| NCT03439982 | Hepatic encephalopathy | Colonoscopy & enema | Phase 1, phase 2 | Recruiting | Canada |
| NCT03796598 | Hepatic encephalopathy | Capsules & enema | Phase 1, phase 2 | Recruiting | United States |
| NCT03408886 | Autism spectrum disorder | Pill (no detail) | Phase 2 | Recruiting | United States |
| NCT03426826 | Autism spectrum disorder | Gastroscope | Phase 1 | Recruiting | United States |
| NCT03829878 | Autism spectrum disorder | Capsules | Phase 2 | Not yet recruiting | United States |
| NCT04182633 | Autism spectrum disorder | Oral administration of FM (no detail) | Phase 2 | Recruiting | United States |
| NCT04246398 | Children with autism | Capsules | Not applicable | Not yet recruiting | Israel |
| NCT03026231 | Parkinson's disease | Capsules | Phase 1, phase 2 | Withdrawn | United States |
| NCT03671785 | Parkinson disease | Capsules | Phase 1 | Recruiting | United States |
| NCT03808389 | Parkinson disease | Nasojejunal | Not applicable | Recruiting | Belgium |
| NCT03876327 | Parkinson disease | Not applicable | Phase 2, phase 3 | Completed | Israel |
| NCT03183869 | Multiple sclerosis | Enema | Phase 2 | Terminated | Canada |
| NCT03594487 | Multiple sclerosis | Colonoscopy | Phase 1 | Recruiting | United States |
| NCT03975413 | Multiple sclerosis | Not applicable | Not applicable | Active, not recruiting | United States |
| NCT04203017 | Multiple sclerosis | Capsules | Phase 1 | Recruiting | Russian Federation |
| NCT03691987 | Chronic fatigue syndrome/myalgic encephalomyelitis | Enema | Phase 2 | Recruiting | Norway |
| NCT04158427 | Chronic fatigue syndrome/myalgic encephalomyelitis | Colonoscopy | Not applicable | Enrolling by invitation | Finland |
| NCT03233100 | Depressive symptoms, anxiety symptoms, gut-brain disorders | Not applicable | Not applicable | Unknown status∗ | China |
| NCT03281044 | Major depressive disorder | Capsules | Phase 2 | Terminated | Switzerland |
| NCT04001439 | Depression in schizophrenia | Capsules | Not applicable | Not yet recruiting | France |
| NCT03998423 | Alzheimer disease | Capsules | Phase 1 | Terminated | United States |
| NCT02889627 | Epilepsy | Microbiota suspension infused into midgut or lower gut (no detail) | Phase 2, phase 3 | Recruiting | China |
| NCT03279224 | Bipolar depression | Colonoscopy | Phase 2, phase 3 | Recruiting | Canada |
| NCT03766321 | Amyotrophic lateral sclerosis | Nasojejunal | Not applicable | Recruiting | Italy |
| NCT04132427 | Pitt-Hopkins syndrome | Oral (no detail) | Phase 2 | Recruiting | United States |
| NCT03416751 | Alcohol abuse | Enema | Phase 1 | Completed | United States |
| NCT03928808 | Anorexia nervosa | Nasogastric tube | Early phase 1 | Suspended | United States |
| NCT02336789 | Disorientation as to people, time and place | Colonoscopy | Not applicable | Unknown status∗ | Israel |
| NCT04014413 | Hepatic encephalopathy, multiple sclerosis, autism, alcohol dependence | Not applicable | Not applicable | Recruiting | China |
∗Study has passed its completion date, and status has not been verified in more than two years. Date from https://clinicaltrials.gov/.