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. 2021 Jan 6;118(3):e2001248118. doi: 10.1073/pnas.2001248118

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Fig. 5. — The distribution of CoNeS for genes underlying inborn errors of neurodevelopment (IEND), according to disease mode of inheritance and mechanism of dominance. (A) The number of genes underlying IEND, according to the mode of disease inheritance. (B) The distribution of CoNeS for autosomal genes underlying IEND, according to their dominant (AD), recessive (AR), or both recessive and dominant (AR/AD) mode of inheritance, relative to autosomal background (AB) genes. (C) The distribution of CoNeS for genes on the X chromosome, relative to AB genes. (D) The distribution of CoNeS for IEND AD genes, according to the mechanism of dominance.