Table 1.

Altered Genes Following ALK3-Fc Treatment in the Rat Blast Injury Model

POD3		POD7		POD14
Genes	Fold change	Genes	Fold change	Genes	Fold change
Tac1	−41722.85	Adipoq	−19.95	Tac1	−12578.31
Col10a1	−883.56	Fgf10	−6.77	Il6	−233.75
Sox2	−699.89	Sparc	−6.21	Bglap	−201.45
Bglap	−312.36	Adipor1	−5.77	Sox2	−140.09
Smad3	−172.49	Vegfa	−5.43	Tert	−111.12
Lep	−152.66	Wnt5a	−5.41	Phex	−91.44
Il6	−102.58	Igf2	−5.40	Il10	−62.01
Mmp9	−97.29	Notch1	−5.14	Cebpa	−56.65
Tert	−55.87	Scarb1	−5.13	Smad3	−46.46
Cxcl1	−49.35	Lrp5	−4.96	Notch1	−42.37
Runx2	−48.41	Smurf1	−4.84	Fgf2	−41.74
Tbx5	−36.58	Fgf1	−4.78	Mmp9	−40.31
Col2a1	−30.07	Ptk2	−4.75	Adipoq	−38.21
Has1	−28.32	Itga1	−4.63	Ibsp	−36.01
Phex	−27.61	Tgfb3	−4.36	Smo	−15.34
Fgf2	−24.31	Jag1	−4.32	Bmp6	−12.79
Tnf	−20.64	Cxcl12	−4.24	Lep	−12.37
Cebpa	−16.54	Sp1	−4.09	Smurf1	−11.59
Pou5f1	−16.16	Flt1	−3.98	Scarb1	−10.94
Col4a3	−13.72	Pdgfa	−3.85	Tnf	−10.27
Smo	−11.97	Myod1	−3.65	Col4a3	−8.39
Notch1	−11.38	Smurf2	−3.51	Sox9	−8.15
Il10	−10.10	Fgf2	−3.48	Alpl	−8.02
Bmp2	−9.49	Angpt2	−3.29	Eng	−7.42
Bmp6	−7.20	Itgav	−3.00	Fgf1	−3.91
Alpl	−5.14	Bmp6	−2.91	Has2	−3.48
Cxcl10	−4.77	Ptch1	−2.87	Fgf10	−3.33
Fgf10	−3.30	Col4a3	−2.84	Sp1	−3.08
Smurf1	−2.95	Kdr	−2.75	Itga1	−2.71
Tgfb3	3.71	Rhoa	−2.58	Comp	2.07
Ptch1	4.12	Hat1	−2.55	Angpt2	4.22
Itga2	6.73	Pou5f1	4.52	Omd	4.36
Ptk2	7.96			Myod1	5.22
Omd	8.40			Lrp5	5.73
Pdgfa	8.85			Cd44	5.81
Hat1	11.16			Tgfb1	5.94
Tgfb1	14.39			Ccl2	7.86
Adipor1	14.40			Pdgfa	8.51
Cd44	15.79			Vegfa	15.30
Bmp4	24.49			Bmp4	15.56
Sparc	26.68			Hdac1	15.66
Comp	34.44			Smurf2	15.90
Angpt2	37.33			Jag1	19.17
Smurf2	66.71			Flt1	23.32
Hdac1	73.24			Sparc	30.91
Jag1	76.74			Gusb	47.09
Myod1	92.58			Itgav	57.60
Itgav	97.71			Col1a1	112.98
Vegfa	100.37			Fabp4	251.24
Flt1	110.52			Kdr	374.42
Lrp5	142.38
Gusb	153.83
Fabp4	196.00
Itgam	512.00
Col1a1	808.03

POD, postoperative day.