Table 3.

Baseline patient characteristics and Responses Categories in the RECIST.

	Non‐ PPI group (n = 42)	PPI group (n = 16)	p‐ value
Median age, y (range)	68 (40‐86)	62 (42‐82)	0.188 a
Gender, n (%)
Male	21 (50)	10 (63)	0.5765 b
Female	21 (50)	6 (38)
Stage
Ⅰ	1 (2)	0	0.8241 c
Ⅱ	1 (2)	0
Ⅲa	5 (12)	1 (6)
Ⅳ	35 (83)	15 (94)
ECOG Performance Status, n (%)
0	21 (50)	8 (50)	0.7633 b
1	23 (48)	7 (44)
2	0 (2)	1 (6)
Combined regimes
XELOX	21 (42)	12 (75)	0.1551 b
mFOLFOX6	21 (42)	4 (25)
Anti hypertensive
Use	7 (17)	3 (19)	1 c
Non‐use	35 (83)	13 (81)
Response
CR	0	0
PR	21	4
SD	17	7
PD	4	5
Objective control rate	50%	25%	0.138 c
Disease control rate	90%	69%	0.097 c

Abbreviations: CR, complete response; PD, progression dessease; PR, partial response; SD, stable disease.

^aMann‐Whitney U test.

^bChi‐square test.

^cFisher's exact test.