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. 2021 Jan 7;10(2):198. doi: 10.3390/jcm10020198

Table 3.

Major studies published regarding the T1MI/T2MI regarding known AF, known CCS, and triggers of T2MI [32,33,34,35,36,37,38].

Authors N (%) Age (Years) T2 Known CCS before MI (%) Known AF
before MI
Anticoagulant at Admission Triggers for Type 2 MI Outcomes
Baron et al. [32] T1MI 17,488 pts 71 ± 12 30.4% (MI) ND 5.3% 1-year mortality T1MI vs. T2MI
13.5% vs. 23.7% p < 0.001
T2MI 1403 pts 76 ± 11 40.1% (MI) ND 10.2% 1. Tachyarrhythmia: 24%
2. Respiratory Failure: 19%
3. Sepsis: 18%
4. Anemia: 13%
Bradyarrhythmia: ND
Multiple provoking conditions: ND
Lambrecht et al. [33] T1MI 360 pts 70 ± 13 ND 8.9% ND All-cause mortality at 3 years T1MI vs. T2MI
31.7% vs. 62.2% p < 0.0001
T2MI 119 pts 75 ± 11 ND 21.0% ND ND
Cediel et al. [34] T1MI 376 pts 66 ND 31.9% ND 2-year mortality T1MI vs. T2MI
19.7% vs. 39.7% p < 0.001
T2MI 194 pts 79 ND 21.1% ND 1. Heart failure: 28%
2. Tachyarrhythmia: 19%
3. Respiratory Failure: 19%
Anaemia: 0%
Bradyarrhythmia: 0%
Multiple provoking conditions: ND
Shah et al. [35] T1MI 1171 pts 68 ± 14 45% ND 4% 1-year mortality T1MI vs. T2MI
16% vs. 37% p < 0.001
T2MI 429 pts 75 ± 13 45% ND 10% ND
Sarkisian et al. [25] T1MI 2673 pts ND ND ND ND ND
T2MI 1089 pts 71 ± 14 17% (MI) 29% ND 1. Sepsis: 30%
2. Heart Failure: 16%
3. AF: 10%
Anaemia: ND
Bradyarrhythmia: 7%
Multiple provoking conditions: 33%
Chapman et al. [36] T1MI 1171 pts 68 ± 14 45% ND 4.5% 5-year mortality T1MI vs. T2MI
31.0% vs. 56.1% p < 0.001
T2MI 429 pts 75 ± 14 45% ND 9.7% 1. Arrhythmia: 19%
2. Pneumonia: 13%
3. Heart Failure: 12%
Anaemia: ND
Bradyarrhythmia: ND
Multiple provoking conditions: ND
Putot et al. [37] T1MI 2036 pts 67 ± ND 20% 7.9% 7.9% In-hospital mortality T1MI vs. T2MI
6.1% vs. 14%, p < 0.001
T2MI 947 pts 81 ± ND 31% 23.7% 23.7% 1. Acute infection: 36%
2. Heart Failure: 34%
3. Anemia: 7.8%
Bradyarrhythmia: ND
Multiple provoking conditions: ND
Putot et al. [38] T1MI 365 pts 72 ± ND 30% ND 15% In-hospital mortality T1MI vs. T2MI
7% vs. 15%, p < 0.001
T2MI 254 pts 82 ± ND 15% ND 27% ND