Table 4.

Major studies published regarding the T1MI/T2MI regarding known AF, known CCS, and triggers of T2MI [39,40,41,42,43,44].

Authors		N (%)	Age (Years) T2	Known CCS before MI (%)	Known AF before MI	Anticoagulant at Admission	Triggers for Type 2 MI	Outcomes
Arora et al. [39]	T1 MI	775 pts	65 ± ND	ND	ND	ND		In-hospital mortality T1MI vs. T2MI 4.7% vs. 17.4%, p < 0.001 30 days mortality after hospital discharge T1MI vs. T2MI 2.2% vs. 11.9%, p < 0.001 1 year mortality after hospital discharge T1MI vs. T2MI 12.4% vs. 34.8%, p < 0.001
	T2 MI	264 pts	73 ± ND	ND	ND	ND	1. Acute infection: 46% 2. Heart Failure: 11% 3. Anemia: 7% Bradyarrhythmia: ND Multiple provoking conditions: ND
Guimaraes et al. [40]	T1 MI	11,647 pts	64 ± ND	ND	ND	ND		2-year mortality T1MI vs. T2MI HR (95% IC): 11.82 (5.71–24.46) p < 0.0001
	T2 MI	847 pts	66 ± ND	ND	ND	ND	1. AF: 22.4% 2. Anemia: 21.1% 3. Hypotension: 14.5% Bradyarrhythmia: ND Multiple provoking conditions: ND
Lopez-Cuenca et al. [41]	T1 MI	707 pts	68 ± 13	36% (MI)	15%	ND		1 year mortality T1MI vs. T2MI Adjusted HR (95% IC): 0.88 (0.50–1.53) p = 0.692
	T2 MI	117 pts	72 ± 12	50% (MI)	44%	ND	ND
Javed et al. [42]	T1 MI	143 pts	65.9 ± 1.6	ND	ND	ND		ND
	T2 MI	64 pts	64.2 ± 2.5	ND	ND	ND	1. Sepsis: 20% 2. Heart Failure: 14.5% 3. Tachyarrthythmia: 13.2% Anaemia: 4% Bradyarrhythmia: ND Multiple provoking conditions: ND
El-Haddad et al. [43]	T1 MI	512 pts	62 (30–97)	ND	ND	ND		In-hospital mortality T1MI vs. T2MI 5.5% vs. 12.5%, p < 0.001
	T2 MI	295 pts	64 (22–90)	ND	ND	ND	1. Sepsis: 26% 2. Hypentensive emergency: 15% 3. Gastrointestinal bleeding: 14.5% 4. Tachyarrthythmia: 14.5% Bradyarrhythmia: ND Multiple provoking conditions: ND
Putot et al. [44]	T1 MI	3710 pts	67 (56–79)	ND	9%	ND		In-hospital mortality T1MI vs. T2MI 5% vs. 11%, p < 0.001 In-hospital cardiovascular mortality T1MI vs. T2MI 5% vs. 9%, p < 0.001
	T2 MI	862 pts	77 (65–84)	ND	19%	ND	1. Sepsis: 36.5% 2. Tachyarrthythmia: 13% 3. Acute Heart failure: 10% Anaemia: 3% Bradyarrhythmia: 2.5% Multiple provoking conditions: ND