Skip to main content
. 2021 Jan 12;13(2):258. doi: 10.3390/cancers13020258

Table 1.

Patient matrix. The table shows a patient matrix of paravermal trans-cerebellar approach vs. other operative approaches with absolute numbers and percentages within the given vertical column provided in brackets for clarity. Other operative approaches (*) comprise of midline (n = 33), supra-cerebellar (n = 2), lateral approach (n = 3) and stereotaxy (n = 1). Odds ratio is provided where applicable. 1 Tumor size volumes were calculated using the ABC/2 estimation formula based on MRI-data [40]. 2 Two patients excluded due to missing information. 3 The other operational positionings include Fukushima, oblique body position, lateral position. 4 Defined as radiological evidence of HOD on MRI; Abbreviations: HOD = hypertrophic olivary degeneration; CMS = cerebellar mutism syndrome; n/a = not applicable.

n = 50 All Patients n = 50 Paravermal Trans-Cerebellar Approach
n = 11		 Other Operative Approaches *
n = 39		 p-Value Odds Ratio
Age (mean ± SD) 22.7 ± 16.9 20.1 ± 17.5 23.5 ± 17.0 0.57
Male sex (n) 30 6 (54.5%) 24 (61.5%) 0.74 0.75
Tumor size 1 (cm3 ± SD) 27.6 ± 20.6 40.8 ± 26.4 23.6 ± 16.9 0.05
Histology:
  • -

    astrocytoma

 19 7 (63.6%) 12 (30.7%) 0.08 3.94
  • -

    ependymoma

 9 1 (9.1%) 8 (20.5%) 0.66 0.39
  • -

    medulloblastoma

 21 3 (27.2%) 18 (46.1%) 0.32 0.44
Chemotherapy 24 4 (36.3%) 20 (51.2%) 0.50 0.54
Radiotherapy 2 27 4 (36.3%) 23 (58.9%) 0.17 0.35
Associated cyst 13 6 (54.5%) 7 (17.9%) 0.02 5.49
Location 4th ventricle 33 8 (72.7%) 25 (64.1%) 0.73 1.49
Operative positioning:
  • -

    Semi-sitting

 30 6 (54.5%) 24 (61.5%) 0.09 0.29
  • -

    Prone

 15 4 (36.3%) 11 (28.2%) 0.71 1.45
  • -

    other 3

 4 3 (27.2%) 1 (2.6%) 0.03 14.25
Dentate nucleus injury 21 8 (72.7%) 13 (33.3%) 0.04 5.33
HOD development 4 10 7 (63.6%) 3 (7.7%) 0.0003 21
Cerebellar mutism
  • -

    all

 12 2 (18.2%) 10 (25.6%) 1.0 0.64
  • -

    <18 years

 12 2 (18.2%) 10 (25.6%) 0.41 0.40